Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania.

31 Aug 2022
Waggle KD, Griffith MP, Zhu L, Cooper VS, Snyder DJ, Srinivasa V, Phan T, Wells A, Snyder GM, Van Tyne D, Harrison LH, Marsh JW

We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.